{"id":135419,"date":"2026-04-03T10:30:05","date_gmt":"2026-04-03T07:30:05","guid":{"rendered":"https:\/\/realitatearutiera.ro\/?p=135419"},"modified":"2026-04-03T10:30:24","modified_gmt":"2026-04-03T07:30:24","slug":"fara-injectii-fara-restrictii-pastila-de-slabit-aprobata-de-fda-care-schimba-regulile","status":"publish","type":"post","link":"https:\/\/realitatearutiera.ro\/?p=135419","title":{"rendered":"F\u0103r\u0103 injec\u021bii, f\u0103r\u0103 restric\u021bii: pastila de sl\u0103bit aprobat\u0103 de FDA care schimb\u0103 regulile"},"content":{"rendered":"\n

O nou\u0103 pastil\u0103 a fost aprobat\u0103 de FDA \u0219i poate fi administrat\u0103 \u00een orice moment al zilei, oferind o solu\u021bie practic\u0103 pentru milioane de persoane care se lupt\u0103 cu obezitatea. Studiile clinice arat\u0103 c\u0103 doza maxim\u0103 poate reduce greutatea corporal\u0103 cu p\u00e2n\u0103 la 25 de kilograme, \u00een timp ce pacien\u021bii au \u00eenregistrat \u0219i \u00eembun\u0103t\u0103\u021biri ale tensiunii arteriale, colesterolului \u0219i nivelului trigliceridelor\"Pastil\u0103<\/p>\n\n\n\n

Pastil\u0103 de sl\u0103bit Foto: Getty images<\/p>\n\n\n\n

Medicamentul, numit orforglipron <\/a>\u0219i comercializat sub denumirea de Foundayo, este un GLP-1 care imit\u0103 un hormon natural ce controleaz\u0103 apetitul \u0219i senza\u021bia de sa\u021bietate, similar cu medicamentele injectabile folosite pe scar\u0103 larg\u0103.<\/p>\n\n\n\n

Spre deosebire de acestea, pastila poate fi administrat\u0103 f\u0103r\u0103 restric\u021bii, f\u0103r\u0103 a fi nevoie de o pauz\u0103 de 30 de minute \u00eenainte de mas\u0103 sau b\u0103uturi, potrivit sciencealert.<\/a><\/p>\n\n\n\n

Foundayo va \u00eencepe s\u0103 fie livrat de luni, iar persoanele cu asigurare medical\u0103 ar putea beneficia de pre\u021buri \u00eencep\u00e2nd de la 25 de dolari pe lun\u0103. Pentru cei care pl\u0103tesc integral, pre\u021burile variaz\u0103 \u00eentre 149 \u0219i 349 de dolari pe lun\u0103, \u00een func\u021bie de doz\u0103.<\/p>\n\n\n\n

Aceast\u0103 pastil\u0103 se al\u0103tur\u0103 Wegovy, pilula oral\u0103 dezvoltat\u0103 de compania Novo Nordisk, care a generat peste 600.000 de re\u021bete \u00een Statele Unite de la aprobarea sa \u00een decembrie.<\/p>\n\n\n\n

FDA a acordat aprobare rapid\u0103 pentru orforglipron \u00een cadrul unui program destinat reducerii timpului de aprobare a medicamentelor, examin\u00e2nd cererea companiei \u00een doar 50 de zile.<\/p>\n\n\n\n

Potrivit publica\u021biei citate, \u00eentr-un studiu clinic efectuat pe peste 3.000 de adul\u021bi cu obezitate,<\/a> participan\u021bii care au primit doza maxim\u0103 de 36 mg de orforglipron au pierdut, \u00een medie, 11,2% din greutatea corporal\u0103 \u2013 aproximativ 25 de kilograme \u2013 pe parcursul a mai mult de 16 luni. \u00cen grupul placebo, pierderea medie de greutate a fost de 2,1%, echivalentul a mai pu\u021bin de 5 kilograme, potrivit New England Journal of Medicine.<\/p>\n\n\n\n

Comparativ cu medicamentele injectabile, pastilele zilnice determin\u0103 o sc\u0103dere mai redus\u0103 \u00een greutate: Zepbound, de la Eli Lilly, genereaz\u0103 o pierdere medie de 21%, iar injectabila Wegovy de la Novo Nordisk \u2013 aproximativ 15%.<\/p>\n\n\n\n

Studiul a ar\u0103tat c\u0103 pacien\u021bii care au utilizat orforglipron au beneficiat \u0219i de \u00eembun\u0103t\u0103\u021biri ale circumferin\u021bei taliei, tensiunii arteriale, nivelului trigliceridelor \u0219i colesterolului.<\/p>\n\n\n\n

Efectele secundare au fost \u00een mare parte gastrointestinale, determin\u00e2nd \u00eentre 5% \u0219i 10% dintre participan\u021bi s\u0103 \u00eentrerup\u0103 tratamentul, comparativ cu aproape 3% \u00een grupul placebo.<\/p>\n\n\n\n

Sursa:adevarul Foto: Getty images<\/p>\n","protected":false},"excerpt":{"rendered":"

O nou\u0103 pastil\u0103 a fost aprobat\u0103 de FDA \u0219i poate fi administrat\u0103 \u00een orice moment al zilei, oferind o solu\u021bie<\/p>\n","protected":false},"author":1,"featured_media":135420,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"spay_email":"","footnotes":"","jetpack_publicize_message":""},"categories":[80],"tags":[],"class_list":["post-135419","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sanatate"],"jetpack_featured_media_url":"https:\/\/realitatearutiera.ro\/wp-content\/uploads\/2026\/04\/index-2.webp","jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p61naM-zeb","jetpack-related-posts":[],"_links":{"self":[{"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=\/wp\/v2\/posts\/135419","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=135419"}],"version-history":[{"count":1,"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=\/wp\/v2\/posts\/135419\/revisions"}],"predecessor-version":[{"id":135421,"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=\/wp\/v2\/posts\/135419\/revisions\/135421"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=\/wp\/v2\/media\/135420"}],"wp:attachment":[{"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=135419"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=135419"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/realitatearutiera.ro\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=135419"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}